Congratulations to North East Thames trainee, James Allinson, first author of a paper in the American Journal of Respiratory and Critical Care Medicine. He and his co-authors analysed data on chronic mucus hypersecretion, smoking and lung function prospectively collected by the MRC National Survey of Health and Development, a nationally representative British cohort followed since birth in 1946. He analysed the longitudinal relationships between smoking and chronic mucus hypersecretion.
The article concludes that chronic mucus hypersecretion amongst middle-aged smokers represents an early developmental phase of COPD. Smoking-related chronic mucus hypersecretion usually resolves following smoking cessation but the longer its duration the greater the FEV1 lost, suggesting the course of chronic mucus hypersecretion across adult life may reflect the underlying course of airway disease activity
Read the full text article here:
Allinson, J. P., Hardy, R., Donaldson, G. C., Shaheen, S. O., Kuh, D., & Wedzicha, J. A. (2015). The Presence of Chronic Mucus Hypersecretion Across Adult Life in Relation to COPD Development. American journal of respiratory and critical care medicine.