Two North East Thames trainees, Richa Singh and Alex Mackay, are authors of a paper, hot off the press, in the journal Respiratory Research. They describe a prospective observational cohort study, examining the impact of exacerbations in non-CF bronchiectasis. A number of outcomes are explored, including PEFR, CAT score, symptom count and CRP. The authors highlight the fact that lung function and symptoms deteriorate between three and four days prior to patients initiating therapy, suggesting a window for earlier detection and treatment of exacerbations. They also point out that the overall burden of these community exacerbations is high, with a median symptom duration of 16 days.
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